| Gene Information | |
|---|---|
| Gene Name | CS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 956 |
| Protein Names | Calsyntenin-3 (Alcadein-beta) (Alc-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BQT9 |
| Gene Card | CLSTN3 |
| Uniprot ID | Q9BQT9 |
| Pfam | PF00028; PF19699 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | According to PubMed:12498782, expressed predominantly in the brain and in kidney. Low levels in heart, skeletal muscle, liver, placenta, pancreas and lung. According to PubMed:12972431, predominant expression in brain, and only marginal in kidney. In brain, present throughout all cortical layers, highest levels in GABAergic neurons (based on morphology and distribution pattern). {ECO:0000269|PubMed:12498782, ECO:0000269|PubMed:12972431}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7302230 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q99JH7}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q99JH7}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q99JH7}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q99JH7}. Postsynapse {ECO:0000250|UniProtKB:Q99JH7}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q99JH7}. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization. {ECO:0000250|UniProtKB:Q99JH7}. |
| Mouse PG classification | NA |
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