| Gene Information | |
|---|---|
| Gene Name | DLGAP5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 846 |
| Protein Names | Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein) (HURP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000126787 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q15398 |
| Gene Card | DLGAP5 |
| Uniprot ID | Q15398 |
| Pfam | PF03359 |
| In ASD | no |
| Allosteric Prediction | no (-0.517244991) |
| Ortholog in Animals | Alpaca_ DLGAP5 ( ortholog_one2one ) Dog_ DLGAP5 ( ortholog_one2one ) GuineaPig_ DLGAP5 ( ortholog_one2one ) Macaque_ DLGAP5 ( ortholog_one2one ) Mouse_ Dlgap5 ( ortholog_one2one ) Pig_ DLGAP5 ( ortholog_one2one ) Rat_ Dlgap5 ( ortholog_one2one ) Rabbit_ DLGAP5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DLGAP4, DLGAP1, DLGAP3, DLGAP2 |
| Tissue | brain, testis |
| Tissue Specificity | Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta. {ECO:0000269|PubMed:12527899}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2274271 rs8010791 rs17128275 rs35954941 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells. |
| Mouse PG classification | NA |
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