| Gene Information | |
|---|---|
| Gene Name | GRS |
| Organism | Homo sapiens (Human) |
| Gene Length | 175 |
| Protein Names | Bcl-2-related protein A1 (Bcl-2-like protein 5) (Bcl2-L-5) (Hemopoietic-specific early response protein) (Protein BFL-1) (Protein GRS) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q16548 |
| Gene Card | BCL2A1 |
| Uniprot ID | Q16548 |
| Pfam | PF00452 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003847(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2VM6 (X-ray 2.20A ) 3I1H (X-ray 2.20A ) 3MQP (X-ray 2.24A ) 4ZEQ (X-ray 1.80A ) 5UUK (X-ray 1.20A ) 5UUL (X-ray 1.33A ) 5UUP (X-ray 1.73A ) 5WHH (X-ray 2.38A ) 5WHI (X-ray 1.69A ) 6E3I (X-ray 1.48A ) 6E3J (X-ray 1.48A ) 6MBB (X-ray 1.59A ) 6MBC (X-ray 1.75A ) 6RJP (X-ray 2.57A ) 6VO4 (X-ray 1.74A ) |
| DBSNP | rs1138357 rs1138358 rs3826007 rs34080999 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:34245648}. |
| Mouse PG classification | NA |
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