| Gene Information | |
|---|---|
| Gene Name | CDH3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 814 |
| Protein Names | Cadherin-15 (Cadherin-14) (Muscle cadherin) (M-cadherin) |
| Target Name | placental cadherin |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000062038 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P55291 |
| Gene Card | CDH15 |
| Uniprot ID | P55291 |
| Pfam | PF01049; PF00028 |
| In ASD | no |
| Allosteric Prediction | no (-0.392163242) |
| Ortholog in Animals | Alpaca_ CDH3 ( ortholog_one2one ) Dog_ CDH3 ( ortholog_one2one ) GuineaPig_ CDH3 ( ortholog_one2one ) Macaque_ CDH3 ( ortholog_one2one ) Mouse_ Cdh3 ( ortholog_one2one ) Pig_ CDH3 ( ortholog_one2one ) Rat_ Cdh3 ( ortholog_one2one ) Rabbit_ CDH3 ( ortholog_one2one ) |
| Ohnologs | DSG2, CDH19, CDH7, CDH20, CDH26, CDH15, DSC2, DSG3, DSC3, DSC1, CDH13, CDH22, CDH2, DSG4, CDH4, CDH10, CDH9, CDH6, CDH24, CDH18, CDH12 |
| Paralogs | CDH7, CDH9, CDH20, CDH4, CDH18, PCDH1, PCDH20, CDH26, CDH19, PCDH9, PCDH11Y, PCDH11X, CDH17, CDHR5, CDHR3, DCHS2, CDH24, CDH23, PCDH7, CDH15, CDHR1, DCHS1, CDH11, CDH8, CDH10, CDH12, CDH13, CDH6, CDH1, CDHR2, CDH22, CDH5, CDH2 |
| Tissue | ovary |
| Tissue Specificity | Expressed in the brain and cerebellum. {ECO:0000269|PubMed:19012874}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs567903921 rs121434539 rs121434540 rs121434541 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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