| Gene Information | |
|---|---|
| Gene Name | CRY1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 586 |
| Protein Names | Cryptochrome-1 |
| Target Name | cryptochrome circadian clock 1 |
| Target Type | Preclinical target |
| Gene Age | 645 ( ENSG00000008405 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q16526 |
| Gene Card | CRY1 |
| Uniprot ID | Q16526 |
| Pfam | PF00875; PF03441 |
| In ASD | no |
| Allosteric Prediction | yes (0.356964437) |
| Ortholog in Animals | Alpaca_ CRY1 ( ortholog_one2one ) Dog_ CRY1 ( ortholog_one2one ) GuineaPig_ CRY1 ( ortholog_one2one ) Macaque_ CRY1 ( ortholog_one2one ) Mouse_ Cry1 ( ortholog_one2one ) Pig_ CRY1 ( ortholog_one2one ) Rat_ Cry1 ( ortholog_one2one ) Rabbit_ CRY1 ( ortholog_one2one ) |
| Ohnologs | CRY2 |
| Paralogs | CRY2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.031851(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus {ECO:0000269|PubMed:22798407, ECO:0000269|PubMed:26431207, ECO:0000269|PubMed:28388406}. Note=Translocated to the nucleus through interaction with other clock proteins such as PER2 or BMAL1. {ECO:0000250|UniProtKB:P97784}. |
| Mouse PG classification | NA |
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