| Gene Information | |
|---|---|
| Gene Name | CRX |
| Organism | Homo sapiens (Human) |
| Gene Length | 299 |
| Protein Names | Cone-rod homeobox protein |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105392 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O43186 |
| Gene Card | CRX |
| Uniprot ID | O43186 |
| Pfam | PF00046; PF03529 |
| In ASD | no |
| Allosteric Prediction | no (-0.917975997) |
| Ortholog in Animals | Alpaca_ CRX ( ortholog_one2one ) Dog_ CRX ( ortholog_one2one ) GuineaPig_ CRX ( ortholog_one2one ) Macaque_ CRX ( ortholog_one2one ) Mouse_ Crx ( ortholog_one2one ) Pig_ CRX ( ortholog_one2one ) Rat_ Crx ( ortholog_one2one ) |
| Ohnologs | OTX1, OTX2 |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | pineal.gland |
| Tissue Specificity | Retina. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs139340178 rs61748436 rs104894672 rs863224863 rs61748438 rs104894671 rs104894673 rs750727986 rs61748441 rs1165723137 rs763651232 rs61748445 rs61748459 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
| Mouse PG classification | HPG |
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