| Gene Information | |
|---|---|
| Gene Name | IMPD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 514 |
| Protein Names | Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P20839 |
| Gene Card | IMPDH1 |
| Uniprot ID | P20839 |
| Pfam | PF00571; PF00478 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.003571(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JCN (X-ray 2.50A ) 7RER (EM 2.60A ) 7RES (EM 3.05A ) 7RFE (EM 2.60A ) 7RFF (EM 2.70A ) 7RFG (EM 2.60A ) 7RFH (EM 3.70A ) 7RFI (EM 2.60A ) 7RGD (EM 3.00A ) 7RGI (EM 3.60A ) 7RGL (EM 2.40A ) 7RGM (EM 2.80A ) 7RGQ (EM 3.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03156, ECO:0000269|PubMed:14766016}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03156, ECO:0000269|PubMed:14766016}. |
| Mouse PG classification | NA |
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