| Gene Information | |
|---|---|
| Gene Name | CRLF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 422 |
| Protein Names | Cytokine receptor-like factor 1 (Cytokine-like factor 1) (CLF-1) (ZcytoR5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000006016 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75462 |
| Gene Card | CRLF1 |
| Uniprot ID | O75462 |
| Pfam | PF09067; PF00041 |
| In ASD | no |
| Allosteric Prediction | no (-0.919058498) |
| Ortholog in Animals | Alpaca_ CRLF1 ( ortholog_one2one ) Dog_ CRLF1 ( ortholog_one2one ) GuineaPig_ CRLF1 ( ortholog_one2one ) Macaque_ CRLF1 ( ortholog_one2one ) Mouse_ Crlf1 ( ortholog_one2one ) Pig_ CRLF1 ( ortholog_one2one ) Rat_ Crlf1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IL13RA2, IL11RA, IL13RA1, CNTFR, IL2RG, CRLF2, IL31RA, IL3RA, IL6ST, IL12RB1, CSF3R, IL12RB2, GHR, CSF2RA, IL6R, IL27RA, IL23R, LIFR, OSMR, IL5RA, EBI3, PRLR, LEPR |
| Tissue | NA |
| Tissue Specificity | Highest levels of expression observed in spleen, thymus, lymph node, appendix, bone marrow, stomach, placenta, heart, thyroid and ovary. Strongly expressed also in fetal lung. {ECO:0000269|PubMed:9686600}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1295488778 rs137853143 rs104894670 rs774359694 rs137853930 rs11672248 rs556029569 rs761982168 rs137853927 rs137853933 rs771459625 rs104894668 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:9686600}. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |