Gene Information
Gene NameCRL2
OrganismHomo sapiens (Human)
Gene Length371
Protein NamesCytokine receptor-like factor 2 (Cytokine receptor-like 2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLP receptor)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9HC73
Gene CardCRLF2
Uniprot IDQ9HC73
PfamNA
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5J11  (X-ray  2.56A  5J12  (X-ray  3.55A 
DBSNP NA 
Subcellular location [CC][Isoform 1]: Cell membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}.;
[Isoform 2]: Secreted {ECO:0000305}.
Mouse PG classificationNA
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