| Gene Information | |
|---|---|
| Gene Name | CRK7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1490 |
| Protein Names | Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NYV4 |
| Gene Card | CDK12 |
| Uniprot ID | Q9NYV4 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:11683387}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.026667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4CXA (X-ray 3.15A ) 4NST (X-ray 2.20A ) 4UN0 (X-ray 3.15A ) 5ACB (X-ray 2.70A ) 6B3E (X-ray 3.06A ) 6CKX (X-ray 2.80A ) 6TD3 (X-ray 3.46A ) 7NXK (X-ray 3.00A ) |
| DBSNP | rs56121596 rs56362165 rs34070318 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11683387}. Nucleus speckle {ECO:0000269|PubMed:11683387}. Note=Colocalized with nuclear speckles throughout interphase. {ECO:0000269|PubMed:11683387}. |
| Mouse PG classification | NA |
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