| Gene Information | |
|---|---|
| Gene Name | CRK |
| Organism | Homo sapiens (Human) |
| Gene Length | 304 |
| Protein Names | Adapter molecule crk (Proto-oncogene c-Crk) (p38) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000167193 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P46108 |
| Gene Card | CRK |
| Uniprot ID | P46108 |
| Pfam | PF00017; PF00018; PF07653 |
| In ASD | no |
| Allosteric Prediction | no (-0.020329538) |
| Ortholog in Animals | Alpaca_ CRK ( ortholog_one2one ) Dog_ CRK ( ortholog_one2one ) GuineaPig_ CRK ( ortholog_one2one ) Macaque_ CRK ( ortholog_one2one ) Mouse_ Crk ( ortholog_one2one ) Pig_ CRK ( ortholog_one2one ) Rat_ Crk ( ortholog_one2one ) |
| Ohnologs | CRKL |
| Paralogs | CRKL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.143713(Mouse);0.007286(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JU5 (NMR - ) 2DVJ (NMR - ) 2EYV (NMR - ) 2EYW (NMR - ) 2EYX (NMR - ) 2EYY (NMR - ) 2EYZ (NMR - ) 2MS4 (NMR - ) 5UL6 (X-ray 1.45A ) 6ATV (X-ray 1.75A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocated to the plasma membrane upon cell adhesion. {ECO:0000250}. |
| Mouse PG classification | NA |
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