| Gene Information | |
|---|---|
| Gene Name | CRHR |
| Organism | Homo sapiens (Human) |
| Gene Length | 444 |
| Protein Names | Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P34998 |
| Gene Card | CRHR1 |
| Uniprot ID | P34998 |
| Pfam | PF00002; PF02793 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe. {ECO:0000269|PubMed:8243652}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2L27 (NMR - ) 3EHS (X-ray 2.76A ) 3EHT (X-ray 3.40A ) 3EHU (X-ray 1.96A ) 4K5Y (X-ray 2.98A ) 4Z9G (X-ray 3.18A ) 6P9X (EM 2.91A ) 6PB0 (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Endosome. Note=Agonist-binding promotes endocytosis. |
| Mouse PG classification | NA |
| click here to return to the previous page | |