Gene Information
Gene NameISLR2
OrganismHomo sapiens (Human)
Gene Length745
Protein NamesImmunoglobulin superfamily containing leucine-rich repeat protein 2 (Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein)
Target NameNA
Target TypeNA
Gene Age332 ( ENSG00000167178 )
Evolutionary StageVertebrata
AlphaFoldDBQ6UXK2
Gene CardISLR2
Uniprot IDQ6UXK2
PfamPF13855
In ASDno
Allosteric Predictionno (-0.786007528)
Ortholog in AnimalsDog_ ISLR2 ( ortholog_one2one )
GuineaPig_ ISLR2 ( ortholog_one2one )
Macaque_ ISLR2 ( ortholog_one2one )
Mouse_ Islr2 ( ortholog_one2one )
Pig_ ISLR2 ( ortholog_one2one )
Rat_ Islr2 ( ortholog_one2one )
OhnologsNA
ParalogsLRRN4CL, ISLR, LRRN4
Tissuebrain, testis
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.005990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3889598 
Subcellular location [CC]Cell membrane {ECO:0000250};
Single-pass membrane protein {ECO:0000250}.
Mouse PG classificationNA
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