Gene Information
Gene NameCREG2
OrganismHomo sapiens (Human)
Gene Length290
Protein NamesProtein CREG2 (Cellular repressor of E1A-stimulated genes 2)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000175874 )
Evolutionary StageEukaryota
AlphaFoldDBQ8IUH2
Gene CardCREG2
Uniprot IDQ8IUH2
PfamNA
In ASDno
Allosteric Predictionno (-1.418721162)
Ortholog in AnimalsAlpaca_ CREG2 ( ortholog_one2one )
Dog_ CREG2 ( ortholog_one2one )
GuineaPig_ CREG2 ( ortholog_one2one )
Macaque_ CREG2 ( ortholog_one2one )
Mouse_ Creg2 ( ortholog_one2one )
Pig_ CREG2 ( ortholog_one2one )
Rat_ Creg2 ( ortholog_one2one )
OhnologsNA
ParalogsCREG1
Tissuebrain, cerebral.cortex, amygdala, brain.meninx, hippocampus, middle.frontal.gyrus, middle.temporal.gyrus, occipital.cortex, occipital.lobe, olfactory.apparatus, parietal.lobe, thalamus
Tissue SpecificityBrain specific mainly in the limbic system and faintly in the spinal cord but not in cerebellum. {ECO:0000269|PubMed:12408961}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11554173 
Subcellular location [CC]Secreted {ECO:0000269|PubMed:12408961}.
Mouse PG classificationNA
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