| Gene Information | |
|---|---|
| Gene Name | CTDP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 961 |
| Protein Names | RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000060069 ) 3 ( ENSG00000282752 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y5B0 |
| Gene Card | CTDP1 |
| Uniprot ID | Q9Y5B0 |
| Pfam | PF09309; PF03031 |
| In ASD | no |
| Allosteric Prediction | no (-0.181805405) |
| Ortholog in Animals | Alpaca_ CTDP1 ( ortholog_one2one ) Dog_ CTDP1 ( ortholog_one2one ) GuineaPig_ CTDP1 ( ortholog_one2one ) Macaque_ CTDP1 ( ortholog_one2one ) Mouse_ Ctdp1 ( ortholog_one2one ) Pig_ CTDP1 ( ortholog_one2one ) Rat_ Ctdp1 ( ortholog_one2one ) Rabbit_ CTDP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:9765293}. |
| Pharmacological Animal Models | 0.019299(Chimpanzee);0.016206(Mouse);NULL(Rat);0.088000(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1J2X (X-ray 2.00A ) 1ONV (NMR - ) 2K7L (NMR - ) |
| DBSNP | rs4799078 rs2279103 rs557503 rs34967023 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22692537}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22692537}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:22692537}. Midbody {ECO:0000269|PubMed:22692537}. Note=Found at centrosomes in prometaphase, at spindle and spindle poles in metaphase and at spindle midzone and midbody in anaphase and telophase-G1 respectively. |
| Mouse PG classification | NA |
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