| Gene Information | |
|---|---|
| Gene Name | IBRDC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 732 |
| Protein Names | E3 ubiquitin-protein ligase RNF19B (EC 2.3.2.31) (IBR domain-containing protein 3) (Natural killer lytic-associated molecule) (RING finger protein 19B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6ZMZ0 |
| Gene Card | RNF19B |
| Uniprot ID | Q6ZMZ0 |
| Pfam | PF01485 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells (PubMed:10438909). Present in natural killer cells (at protein level) (PubMed:10912506). Ubiquitously expressed with high expression in testis (PubMed:27485036). {ECO:0000269|PubMed:10438909, ECO:0000269|PubMed:10912506, ECO:0000269|PubMed:27485036}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic granule membrane {ECO:0000269|PubMed:10438909}; Multi-pass membrane protein {ECO:0000269|PubMed:10438909}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:27485036}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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