| Gene Information | |
|---|---|
| Gene Name | CHRNB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 458 |
| Protein Names | Neuronal acetylcholine receptor subunit beta-3 |
| Target Name | neuronal acetylcholine (nach) receptor subunits |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000147432 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q05901 |
| Gene Card | CHRNB3 |
| Uniprot ID | Q05901 |
| Pfam | PF02931; PF02932 |
| In ASD | no |
| Allosteric Prediction | yes (0.60721947) |
| Ortholog in Animals | Alpaca_ CHRNB3 ( ortholog_one2one ) Dog_ CHRNB3 ( ortholog_one2one ) GuineaPig_ CHRNB3 ( ortholog_one2one ) Macaque_ CHRNB3 ( ortholog_one2one ) Mouse_ Chrnb3 ( ortholog_one2one ) Pig_ CHRNB3 ( ortholog_one2one ) Rat_ Chrnb3 ( ortholog_one2one ) Rabbit_ CHRNB3 ( ortholog_one2one ) |
| Ohnologs | CHRNA4, CHRNA5, CHRNB2 |
| Paralogs | CHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, GABRP, HTR3C, HTR3D, GABRG1, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, GABRA3, HTR3A, ZACN, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 8A5U (X-ray 2.40A ) |
| DBSNP | rs35327613 |
| Subcellular location [CC] | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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