| Gene Information | |
|---|---|
| Gene Name | CD80 |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80) |
| Target Name | activation b7-1 antigen |
| Target Type | Successful target |
| Gene Age | 168 ( ENSG00000121594 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P33681 |
| Gene Card | CD80 |
| Uniprot ID | P33681 |
| Pfam | PF08205; PF07686 |
| In ASD | no |
| Allosteric Prediction | yes (1.089367139) |
| Ortholog in Animals | Alpaca_ CD80 ( ortholog_one2one ) Dog_ CD80 ( ortholog_one2one ) Macaque_ CD80 ( ortholog_one2one ) Mouse_ Cd80 ( ortholog_one2one ) Pig_ CD80 ( ortholog_one2one ) Rat_ Cd80 ( ortholog_one2one ) Rabbit_ CD80 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RFPL4B, RFPL2, RFPL3, RFPL1, CD86, RNF135, RNF152, RFPL4AL1, RFPL4A, SPRYD4, PDCD1LG2, CD274 |
| Tissue | NA |
| Tissue Specificity | Expressed on activated B-cells, macrophages and dendritic cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002419(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DR9 (X-ray 3.00A ) 1I8L (X-ray 3.00A ) 7TPS (X-ray 3.15A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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