| Gene Information | |
|---|---|
| Gene Name | PSF |
| Organism | Homo sapiens (Human) |
| Gene Length | 707 |
| Protein Names | Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P23246 |
| Gene Card | SFPQ |
| Uniprot ID | P23246 |
| Pfam | PF08075; PF00076 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.0125(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4WII (X-ray 2.05A ) 4WIJ (X-ray 3.49A ) 4WIK (X-ray 3.00A ) 5WPA (X-ray 2.29A ) 6NCQ (X-ray 1.90A ) 6OWJ (X-ray 1.94A ) 6WMZ (X-ray 2.85A ) 7LRQ (X-ray 2.30A ) 7LRU (X-ray 1.60A ) 7PU5 (X-ray 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:25765647}. Nucleus matrix {ECO:0000269|PubMed:10653975, ECO:0000269|PubMed:19439179, ECO:0000269|PubMed:9848648}. Cytoplasm {ECO:0000269|PubMed:19439179}. Note=Predominantly in nuclear matrix. {ECO:0000269|PubMed:19439179}. |
| Mouse PG classification | NA |
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