| Gene Information | |
|---|---|
| Gene Name | CPT1C |
| Organism | Homo sapiens (Human) |
| Gene Length | 803 |
| Protein Names | Carnitine O-palmitoyltransferase 1, brain isoform (CPT1-B) (EC 2.3.1.21) (CPT IC) (Carnitine O-palmitoyltransferase I, brain isoform) (CPTI-B) (Carnitine palmitoyltransferase 1C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000169169 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8TCG5 |
| Gene Card | CPT1C |
| Uniprot ID | Q8TCG5 |
| Pfam | PF00755; PF16484 |
| In ASD | no |
| Allosteric Prediction | no (-0.189278962) |
| Ortholog in Animals | Alpaca_ CPT1C ( ortholog_one2one ) Dog_ CPT1C ( ortholog_one2one ) GuineaPig_ CPT1C ( ortholog_one2one ) Macaque_ CPT1C ( ortholog_one2one ) Mouse_ Cpt1c ( ortholog_one2one ) Pig_ CPT1C ( ortholog_one2one ) Rat_ Cpt1c ( ortholog_one2one ) |
| Ohnologs | CPT1B, CPT1A |
| Paralogs | CPT1A, CPT1B, CPT2, CHAT, CRAT, CROT |
| Tissue | brain |
| Tissue Specificity | Expressed predominantly in brain and testis. Expressed in motor neurons. {ECO:0000269|PubMed:12376098, ECO:0000269|PubMed:25751282}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2M76 (NMR - ) |
| DBSNP | rs786204767 |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Synapse {ECO:0000250|UniProtKB:Q8BGD5}. Cell projection, dendrite {ECO:0000269|PubMed:25751282}. Cell projection, axon {ECO:0000269|PubMed:25751282}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8BGD5}. Note=Localized in the soma and dendritic and axonal projections. {ECO:0000269|PubMed:25751282}. |
| Mouse PG classification | LPG |
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