| Gene Information | |
|---|---|
| Gene Name | OPN4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 478 |
| Protein Names | Melanopsin (Opsin-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122375 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UHM6 |
| Gene Card | OPN4 |
| Uniprot ID | Q9UHM6 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.318082421) |
| Ortholog in Animals | Alpaca_ OPN4 ( ortholog_one2one ) Dog_ OPN4 ( ortholog_one2one ) GuineaPig_ OPN4 ( ortholog_one2one ) Macaque_ OPN4 ( ortholog_one2one ) Mouse_ Opn4 ( ortholog_one2one ) Pig_ OPN4 ( ortholog_one2one ) Rat_ Opn4 ( ortholog_one2one ) Rabbit_ OPN4 ( ortholog_one2one ) |
| Ohnologs | OPN3, OPN5, RHO, RRH |
| Paralogs | OPN3, OPN1MW, OPN1SW, OPN1LW, RHO, OPN1MW3, OPN1MW2, RRH, OPN5 |
| Tissue | NA |
| Tissue Specificity | Expressed in the retina. {ECO:0000269|PubMed:10632589}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2675703 rs1079610 rs12262894 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9QXZ9}; Multi-pass membrane protein {ECO:0000255}. Cell projection, axon {ECO:0000250|UniProtKB:Q9QXZ9}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9QXZ9}. Perikaryon {ECO:0000250|UniProtKB:Q9QXZ9}. |
| Mouse PG classification | NA |
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