| Gene Information | |
|---|---|
| Gene Name | CPQ |
| Organism | Homo sapiens (Human) |
| Gene Length | 472 |
| Protein Names | Carboxypeptidase Q (EC 3.4.17.-) (Lysosomal dipeptidase) (Plasma glutamate carboxypeptidase) |
| Target Name | carboxypeptidase q |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000104324 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y646 |
| Gene Card | CPQ |
| Uniprot ID | Q9Y646 |
| Pfam | PF04389 |
| In ASD | no |
| Allosteric Prediction | no (-0.106481864) |
| Ortholog in Animals | Alpaca_ CPQ ( ortholog_one2one ) Dog_ CPQ ( ortholog_one2one ) GuineaPig_ CPQ ( ortholog_one2one ) Macaque_ CPQ ( ortholog_one2one ) Mouse_ Cpq ( ortholog_one2one ) Pig_ CPQ ( ortholog_one2one ) Rat_ Cpq ( ortholog_one2one ) Rabbit_ CPQ ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles, liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level). {ECO:0000269|PubMed:10206990}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34088584 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:10206990}. Golgi apparatus {ECO:0000269|PubMed:10206990}. Lysosome {ECO:0000250}. Secreted {ECO:0000269|PubMed:10206990}. Note=Secretion is stimulated by TSH/thyroid-stimulating hormone, INS/insulin and SST/somatostatin. {ECO:0000250}. |
| Mouse PG classification | NA |
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