Gene Information
Gene NameCMBL
OrganismHomo sapiens (Human)
Gene Length245
Protein NamesCarboxymethylenebutenolidase homolog (EC 3.1.-.-)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000164237 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ96DG6
Gene CardCMBL
Uniprot IDQ96DG6
PfamPF01738
In ASDno
Allosteric Predictionno (-0.740110415)
Ortholog in AnimalsAlpaca_ CMBL ( ortholog_one2one )
Dog_ CMBL ( ortholog_one2one )
GuineaPig_ CMBL ( ortholog_one2one )
Macaque_ CMBL ( ortholog_one2one )
Mouse_ Cmbl ( ortholog_one2one )
Pig_ CMBL ( ortholog_one2one )
Rat_ Cmbl ( ortholog_one2one )
Rabbit_ CMBL ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level). {ECO:0000269|PubMed:20177059}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs35489000 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:20177059}.
Mouse PG classificationNA
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