Gene Information
Gene NameTRIM54
OrganismHomo sapiens (Human)
Gene Length358
Protein NamesTripartite motif-containing protein 54 (Muscle-specific RING finger protein) (MuRF) (Muscle-specific RING finger protein 3) (MuRF-3) (MuRF3) (RING finger protein 30)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000138100 )
Evolutionary StageEukaryota
AlphaFoldDBQ9BYV2
Gene CardTRIM54
Uniprot IDQ9BYV2
PfamPF00643; PF13445
In ASDno
Allosteric Predictionno (-0.711342523)
Ortholog in AnimalsAlpaca_ TRIM54 ( ortholog_one2one )
Dog_ TRIM54 ( ortholog_one2one )
GuineaPig_ TRIM54 ( ortholog_one2one )
Macaque_ TRIM54 ( ortholog_one2one )
Mouse_ Trim54 ( ortholog_one2one )
Rat_ Trim54 ( ortholog_one2one )
OhnologsNA
ParalogsTRIM42, TRIM13, TRIM31, TRIM49B, TRIM49C, TRIM49, TRIM33, TRIM69, TRIM71, TRIM77, TRIM28, TRIM3, TRIM46, TRIM58, TRIM38, TRIM5, TRIM37, MID1, TRIM7, TRIM36, TRIM44, TRIML2, TRIM2, TRIM63, TRIM73, TRIM74, TRIM65, TRIML1, MID2, TRIM32, TRIM14, TRIM34, TRIM52, TRIM41, TRIM11, PML, TRIM43, TRIM43B, TRIM21, TRIM6, TRIM27, TRIM40, TRIM51G, TRIM51, TRIM9, TRIM67, TRIM25, TRIM49D1, TRIM48, TRIM49D2, TRIM68, TRIM17, TRIM24, TRIM64C, TRIM64, TRIM64B, TRIM60, TRIM61, TRIM4, TRIM10, BSPRY, TRIM56, TRIM29, TRIM8, MEFV, TRIM15, TRIM22, TRIM35, TRIM16, TRIM47, TRIM45, TRIM72, TRIM62, TRIM50, TRIM75, TRIM66, RNF39, TRIM26, TRIM39, TRIM55
Tissueheart, skeletal.muscle
Tissue SpecificitySpecifically expressed in heart and skeletal muscle. {ECO:0000269|PubMed:11243782}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3Q1D  (X-ray  2.15A  ) 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity). {ECO:0000250}.
Mouse PG classificationNA
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