| Gene Information | |
|---|---|
| Gene Name | CPF |
| Organism | Homo sapiens (Human) |
| Gene Length | 541 |
| Protein Names | Nuclear receptor subfamily 5 group A member 2 (Alpha-1-fetoprotein transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Hepatocytic transcription factor) (Liver receptor homolog 1) (LRH-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O00482 |
| Gene Card | NR5A2 |
| Uniprot ID | O00482 |
| Pfam | PF00104; PF00105 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003990(Rat);0.06(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1YOK (X-ray 2.50A ) 1YUC (X-ray 1.90A ) 1ZDU (X-ray 2.50A ) 2A66 (X-ray 2.20A ) 3PLZ (X-ray 1.75A ) 3TX7 (X-ray 2.76A ) 4DOR (X-ray 1.90A ) 4DOS (X-ray 2.00A ) 4IS8 (X-ray 2.78A ) 4ONI (X-ray 1.80A ) 4PLD (X-ray 1.75A ) 4PLE (X-ray 1.75A ) 4RWV (X-ray 1.86A ) 5L0M (X-ray 2.20A ) 5L11 (X-ray 1.85A ) 5SYZ (X-ray 1.93A ) 5UNJ (X-ray 1.96A ) 6OQX (X-ray 2.00A ) 6OQY (X-ray 2.23A ) 6OR1 (X-ray 2.17A ) 6VC2 (X-ray 1.70A ) 6VIF (X-ray 2.26A ) 7JYD (X-ray 2.30A ) 7JYE (X-ray 2.55A ) 7TT8 (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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