| Gene Information | |
|---|---|
| Gene Name | ECHDC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 303 |
| Protein Names | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000134463 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96DC8 |
| Gene Card | ECHDC3 |
| Uniprot ID | Q96DC8 |
| Pfam | PF00378 |
| In ASD | no |
| Allosteric Prediction | no (-1.4836551) |
| Ortholog in Animals | Alpaca_ ECHDC3 ( ortholog_one2one ) Dog_ ECHDC3 ( ortholog_one2one ) GuineaPig_ ECHDC3 ( ortholog_one2one ) Macaque_ ECHDC3 ( ortholog_one2one ) Mouse_ Echdc3 ( ortholog_one2one ) Pig_ ECHDC3 ( ortholog_one2one ) Rat_ Echdc3 ( ortholog_one2one ) Rabbit_ ECHDC3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ECI1, ECHS1, AUH, ECH1, CDY1, CDYL, CDY2A, CDY2B, CDY1B, CDYL2, ECHDC2, HIBCH, ECHDC1 |
| Tissue | NA |
| Tissue Specificity | Expressed in adipocytes (PubMed:31010960). Expressed in blood cells, with higher expression in patients with low coronary lesions (PubMed:27586541). {ECO:0000269|PubMed:27586541, ECO:0000269|PubMed:31010960}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2VX2 (X-ray 2.30A ) |
| DBSNP | rs4750090 rs7910140 rs35986488 |
| Subcellular location [CC] | Mitochondrion {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |