| Gene Information | |
|---|---|
| Gene Name | CPA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 421 |
| Protein Names | Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000163751 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UI42 |
| Gene Card | CPA4 |
| Uniprot ID | Q9UI42 |
| Pfam | PF00246; PF02244 |
| In ASD | no |
| Allosteric Prediction | no (-0.198079307) |
| Ortholog in Animals | Alpaca_ CPA3 ( ortholog_one2one ) Dog_ CPB1 ( ortholog_one2one ) GuineaPig_ CPA3 ( ortholog_one2one ) Macaque_ CPA3 ( ortholog_one2one ) Mouse_ Cpa3 ( ortholog_one2one ) Rat_ Cpa3 ( ortholog_one2one ) Rabbit_ CPA3 ( ortholog_one2one ) |
| Ohnologs | CPB2, CPA1, CPA4, CPA2, CPA5, CPA6 |
| Paralogs | CPO, CPB1, CPA2, CPA6, CPA4, CPB2, CPA5, CPA1 |
| Tissue | NA |
| Tissue Specificity | Fetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);0.200000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BO9 (X-ray 1.60A ) 2BOA (X-ray 2.20A ) 2PCU (X-ray 1.60A ) 4A94 (X-ray 1.70A ) 4BD9 (X-ray 2.20A ) |
| DBSNP | rs34587586 rs3735051 rs3735053 rs2171492 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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