| Gene Information | |
|---|---|
| Gene Name | CPA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 419 |
| Protein Names | Carboxypeptidase A1 (EC 3.4.17.1) |
| Target Name | carboxypeptidase a1 |
| Target Type | Literature-reported target |
| Gene Age | 1292 ( ENSG00000091704 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P15085 |
| Gene Card | CPA1 |
| Uniprot ID | P15085 |
| Pfam | PF00246; PF02244 |
| In ASD | yes |
| Allosteric Prediction | no (-0.230732657) |
| Ortholog in Animals | Alpaca_ CPA1 ( ortholog_one2one ) Dog_ CPA1 ( ortholog_one2one ) GuineaPig_ CPA1 ( ortholog_one2one ) Macaque_ CPA1 ( ortholog_one2one ) Mouse_ Cpa1 ( ortholog_one2one ) Pig_ CPA1 ( ortholog_one2one ) Rat_ Cpa1 ( ortholog_one2one ) Rabbit_ CPA1 ( ortholog_one2one ) |
| Ohnologs | CPB1, CPA3 |
| Paralogs | CPO, CPB1, CPA2, CPA6, CPA3, CPA4, CPB2, CPA5 |
| Tissue | pancreas |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2V77 (X-ray 1.60A ) 3FJU (X-ray 1.60A ) 4UEE (X-ray 2.27A ) 4UEF 4UEZ (X-ray 2.29A ) 4UF4 5OM9 (X-ray 1.80A ) 6I6Z (X-ray 1.72A ) |
| DBSNP | rs34474469 rs17849959 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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