Gene Information
Gene NameCP110
OrganismHomo sapiens (Human)
Gene Length1012
Protein NamesCentriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (CP110) (Cep110)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO43303
Gene CardCCP110
Uniprot IDO43303
PfamNA
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighly expressed in testis. Detected at intermediate levels in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:12361598}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs16972129  rs3751821  rs226891  rs11645625  rs7190666 
Subcellular location [CC]Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:12361598, ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:16760425, ECO:0000269|PubMed:17681131, ECO:0000269|PubMed:17719545, ECO:0000269|PubMed:20596027, ECO:0000269|PubMed:21620453, ECO:0000269|PubMed:30375385}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:30375385}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q7TSH4}. Note=Recruited early and then associates with the growing distal tips. Recruited to the mother centriole by KIF24 (PubMed:21620453). Removed from centrioles by TTBK2, leading to initiation of ciliogenesis and localizes only to the daughter centriole in ciliated cells. In cytotoxic T lymphocytes remains associated with the mother centriole during docking of the centrosome at the immunological synapse upon target contact (By similarity). Recruited at the distal end of the mother centriole by MPHOSPH9 (PubMed:30375385). {ECO:0000250|UniProtKB:Q7TSH4, ECO:0000269|PubMed:21620453, ECO:0000269|PubMed:30375385}.
Mouse PG classificationNA
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