| Gene Information | |
|---|---|
| Gene Name | COX4I1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 169 |
| Protein Names | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1) |
| Target Name | cytochrome c oxidase subunit 4 isoform 1, mitochondrial |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000131143 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P13073 |
| Gene Card | COX4I1 |
| Uniprot ID | P13073 |
| Pfam | PF02936 |
| In ASD | no |
| Allosteric Prediction | no (-0.221337566) |
| Ortholog in Animals | Alpaca_ COX4I1 ( ortholog_one2one ) Dog_ COX4I1 ( ortholog_one2one ) GuineaPig_ COX4I1 ( ortholog_one2one ) Macaque_ COX4I1 ( ortholog_one2one ) Mouse_ Cox4i1 ( ortholog_one2one ) Pig_ COX4I1 ( ortholog_one2one ) Rat_ Cox4i1 ( ortholog_one2one ) Rabbit_ COX4I1 ( ortholog_one2one ) |
| Ohnologs | COX4I2 |
| Paralogs | COX4I2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.249537(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5Z62 (EM 3.60A ) |
| DBSNP | rs11557187 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:30030519}; Single-pass membrane protein {ECO:0000269|PubMed:30030519}. |
| Mouse PG classification | NA |
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