| Gene Information | |
|---|---|
| Gene Name | COQ5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000110871 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q5HYK3 |
| Gene Card | COQ5 |
| Uniprot ID | Q5HYK3 |
| Pfam | PF01209 |
| In ASD | no |
| Allosteric Prediction | no (-1.018534378) |
| Ortholog in Animals | Alpaca_ COQ5 ( ortholog_one2one ) Dog_ COQ5 ( ortholog_one2one ) GuineaPig_ COQ5 ( ortholog_one2one ) Macaque_ COQ5 ( ortholog_one2one ) Mouse_ Coq5 ( ortholog_one2one ) Pig_ COQ5 ( ortholog_one2one ) Rat_ Coq5 ( ortholog_one2one ) Rabbit_ COQ5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | METTL7B, AS3MT, METTL27, METTL7A |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in liver, lung, placenta and skeletal muscle. {ECO:0000269|PubMed:25152161}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);0.016667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3742049 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000255|HAMAP-Rule:MF_03191, ECO:0000269|PubMed:25152161}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03191, ECO:0000269|PubMed:25152161}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03191, ECO:0000269|PubMed:25152161}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |