| Gene Information | |
|---|---|
| Gene Name | COPZ2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 210 |
| Protein Names | Coatomer subunit zeta-2 (Zeta-2-coat protein) (Zeta-2 COP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000005243 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9P299 |
| Gene Card | COPZ2 |
| Uniprot ID | Q9P299 |
| Pfam | PF01217 |
| In ASD | no |
| Allosteric Prediction | no (-0.471684329) |
| Ortholog in Animals | Alpaca_ COPZ2 ( ortholog_one2one ) Dog_ COPZ2 ( ortholog_one2one ) GuineaPig_ COPZ2 ( ortholog_one2one ) Macaque_ COPZ2 ( ortholog_one2one ) Mouse_ Copz2 ( ortholog_one2one ) Pig_ COPZ2 ( ortholog_one2one ) Rat_ Copz2 ( ortholog_one2one ) Rabbit_ COPZ2 ( ortholog_one2one ) |
| Ohnologs | COPZ1 |
| Paralogs | COPZ1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Shows a significant preference for ERGIC and cis-Golgi apparatus compared with trans-Golgi network. {ECO:0000250}. |
| Mouse PG classification | NA |
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