| Gene Information | |
|---|---|
| Gene Name | COPS7A |
| Organism | Homo sapiens (Human) |
| Gene Length | 275 |
| Protein Names | COP9 signalosome complex subunit 7a (SGN7a) (Signalosome subunit 7a) (Dermal papilla-derived protein 10) (JAB1-containing signalosome subunit 7a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000111652 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBW8 |
| Gene Card | COPS7A |
| Uniprot ID | Q9UBW8 |
| Pfam | PF18392; PF01399 |
| In ASD | no |
| Allosteric Prediction | no (-0.061930571) |
| Ortholog in Animals | Alpaca_ COPS7A ( ortholog_one2one ) Dog_ COPS7A ( ortholog_one2one ) GuineaPig_ COPS7A ( ortholog_one2one ) Macaque_ COPS7A ( ortholog_one2one ) Mouse_ Cops7a ( ortholog_one2one ) Pig_ COPS7A ( ortholog_one2one ) Rat_ Cops7a ( ortholog_one2one ) Rabbit_ COPS7A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EIF3M, COPS7B |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed at high level in brain, heart and skeletal muscle. {ECO:0000269|PubMed:12020345}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.015304(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4D10 (X-ray 3.80A ) 4D18 (X-ray 4.08A ) 4WSN (X-ray 5.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9535219}. Nucleus {ECO:0000269|PubMed:9535219}. |
| Mouse PG classification | NA |
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