| Gene Information | |
|---|---|
| Gene Name | COPS4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 406 |
| Protein Names | COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000138663 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BT78 |
| Gene Card | COPS4 |
| Uniprot ID | Q9BT78 |
| Pfam | PF18420; PF01399 |
| In ASD | no |
| Allosteric Prediction | no (-0.399043051) |
| Ortholog in Animals | Alpaca_ COPS4 ( ortholog_one2one ) GuineaPig_ COPS4 ( ortholog_one2one ) Macaque_ COPS4 ( ortholog_one2one ) Mouse_ Cops4 ( ortholog_one2one ) Pig_ COPS4 ( ortholog_one2one ) Rat_ Cops4 ( ortholog_one2one ) Rabbit_ COPS4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PSMD12 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.029028(Mouse);0.030748(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4D0P (X-ray 1.60A ) 4D10 (X-ray 3.80A ) 4D18 (X-ray 4.08A ) 4WSN (X-ray 5.50A ) 6R6H (EM 8.40A ) 6R7F (EM 8.20A ) 6R7H (EM 8.80A ) 6R7I (EM 5.90A ) 6R7N (EM 6.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9535219}. Nucleus {ECO:0000269|PubMed:9535219}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000269|PubMed:21102408}. |
| Mouse PG classification | NA |
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