Gene Information
Gene NameCOPS1
OrganismHomo sapiens (Human)
Gene Length491
Protein NamesCOP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ13098
Gene CardGPS1
Uniprot IDQ13098
PfamPF01399; PF10602
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed. {ECO:0000269|PubMed:8943324}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.030320(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4D10  (X-ray  3.80A  4D18  (X-ray  4.08A  4WSN  (X-ray  5.50A  6R6H  (EM  8.40A  6R7F  (EM  8.20A  6R7H  (EM  8.80A  6R7I  (EM  5.90A  6R7N  (EM  6.50A 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:9535219}. Nucleus {ECO:0000269|PubMed:9535219}.
Mouse PG classificationNA
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