| Gene Information | |
|---|---|
| Gene Name | COPE |
| Organism | Homo sapiens (Human) |
| Gene Length | 308 |
| Protein Names | Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105669 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14579 |
| Gene Card | COPE |
| Uniprot ID | O14579 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.511935439) |
| Ortholog in Animals | Alpaca_ COPE ( ortholog_one2one ) Dog_ COPE ( ortholog_one2one ) GuineaPig_ COPE ( ortholog_one2one ) Macaque_ COPE ( ortholog_one2one ) Mouse_ Cope ( ortholog_one2one ) Pig_ COPE ( ortholog_one2one ) Rat_ Cope ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6TZT (X-ray 3.06A ) 6U3V (X-ray 2.96A ) |
| DBSNP | rs2231987 rs10330 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000250}. |
| Mouse PG classification | NA |
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