| Gene Information | |
|---|---|
| Gene Name | COOL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 776 |
| Protein Names | Rho guanine nucleotide exchange factor 6 (Alpha-Pix) (COOL-2) (PAK-interacting exchange factor alpha) (Rac/Cdc42 guanine nucleotide exchange factor 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15052 |
| Gene Card | ARHGEF6 |
| Uniprot ID | Q15052 |
| Pfam | PF16523; PF00307; PF00169; PF00621; PF07653 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1UJY (NMR - ) 1WYR (NMR - ) |
| DBSNP | rs5974620 |
| Subcellular location [CC] | Cell projection, lamellipodium {ECO:0000250}. |
| Mouse PG classification | NA |
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