| Gene Information | |
|---|---|
| Gene Name | COMMD8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 183 |
| Protein Names | COMM domain-containing protein 8 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000169019 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NX08 |
| Gene Card | COMMD8 |
| Uniprot ID | Q9NX08 |
| Pfam | PF07258 |
| In ASD | no |
| Allosteric Prediction | no (-0.911665296) |
| Ortholog in Animals | Alpaca_ COMMD8 ( ortholog_one2one ) Dog_ COMMD8 ( ortholog_one2one ) GuineaPig_ COMMD8 ( ortholog_one2one ) Macaque_ COMMD8 ( ortholog_one2one ) Mouse_ Commd8 ( ortholog_one2one ) Pig_ COMMD8 ( ortholog_one2one ) Rat_ Commd8 ( ortholog_one2one ) Rabbit_ COMMD8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | COMMD7, COMMD6 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest expression in thyroid. {ECO:0000269|PubMed:15799966}. |
| Pharmacological Animal Models | 0.081242(Chimpanzee);0.162680(Mouse);0.001425(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35444219 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}. |
| Mouse PG classification | NA |
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