| Gene Information | |
|---|---|
| Gene Name | COMMD5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 224 |
| Protein Names | COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000170619 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9GZQ3 |
| Gene Card | COMMD5 |
| Uniprot ID | Q9GZQ3 |
| Pfam | PF07258 |
| In ASD | no |
| Allosteric Prediction | no (-0.651557536) |
| Ortholog in Animals | Alpaca_ COMMD5 ( ortholog_one2one ) Dog_ COMMD5 ( ortholog_one2one ) GuineaPig_ COMMD5 ( ortholog_one2one ) Macaque_ COMMD5 ( ortholog_one2one ) Mouse_ Commd5 ( ortholog_one2one ) Pig_ COMMD5 ( ortholog_one2one ) Rat_ Commd5 ( ortholog_one2one ) Rabbit_ COMMD5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, stomach, jejunum, kidney, liver, and adrenal gland. Expression was generally higher in adult organs than in fetal tissues, particularly in heart, kidney, and liver. {ECO:0000269|PubMed:10918053, ECO:0000269|PubMed:15799966}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.030071(Rat);0.042279(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1209879 rs421427 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}. |
| Mouse PG classification | NA |
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