| Gene Information | |
|---|---|
| Gene Name | PRSS21 |
| Organism | Homo sapiens (Human) |
| Gene Length | 314 |
| Protein Names | Testisin (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP-1) (Serine protease 21) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000007038 ) 3 ( ENSG00000282838 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y6M0 |
| Gene Card | PRSS21 |
| Uniprot ID | Q9Y6M0 |
| Pfam | PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.911260727) |
| Ortholog in Animals | Alpaca_ PRSS21 ( ortholog_one2one ) Mouse_ Prss21 ( ortholog_one2one ) Pig_ PRSS21 ( ortholog_one2one ) Rat_ Prss21 ( ortholog_one2one ) |
| Ohnologs | PRSS36, TMPRSS2, TMPRSS6, TMPRSS11E, TMPRSS4, TMPRSS5, TMPRSS11F |
| Paralogs | TMPRSS15, TMPRSS6, HPN, TMPRSS11E, ST14, TMPRSS3, TMPRSS13, TMPRSS11D, TMPRSS2, PRSS22, TMPRSS11A, TMPRSS7, TMPRSS11B, TMPRSS9, TMPRSS5, TMPRSS11F, PRSS41 |
| Tissue | testis |
| Tissue Specificity | Expressed predominantly in premeiotic testicular germ cells, mostly late pachytene and diplotene spermatocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2072273 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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