| Gene Information | |
|---|---|
| Gene Name | DDIT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 169 |
| Protein Names | DNA damage-inducible transcript 3 protein (DDIT-3) (C/EBP zeta) (C/EBP-homologous protein) (CHOP) (C/EBP-homologous protein 10) (CHOP-10) (CCAAT/enhancer-binding protein homologous protein) (Growth arrest and DNA damage-inducible protein GADD153) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000175197 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P35638 |
| Gene Card | DDIT3 |
| Uniprot ID | P35638 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.174981743) |
| Ortholog in Animals | Alpaca_ DDIT3 ( ortholog_one2one ) Dog_ DDIT3 ( ortholog_one2one ) GuineaPig_ DDIT3 ( ortholog_one2one ) Macaque_ DDIT3 ( ortholog_one2one ) Mouse_ Ddit3 ( ortholog_one2one ) Pig_ DDIT3 ( ortholog_one2one ) Rat_ Ddit3 ( ortholog_one2one ) Rabbit_ DDIT3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002354(Rat);0.036364(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:29083303}. Nucleus {ECO:0000269|PubMed:29083303, ECO:0000269|PubMed:33384352}. Note=Present in the cytoplasm under non-stressed conditions and ER stress leads to its nuclear accumulation. {ECO:0000269|PubMed:29083303}. |
| Mouse PG classification | NA |
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