| Gene Information | |
|---|---|
| Gene Name | MVB12B |
| Organism | Homo sapiens (Human) |
| Gene Length | 319 |
| Protein Names | Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000196814 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H7P6 |
| Gene Card | MVB12B |
| Uniprot ID | Q9H7P6 |
| Pfam | PF10240 |
| In ASD | no |
| Allosteric Prediction | no (-0.847212878) |
| Ortholog in Animals | Alpaca_ MVB12B ( ortholog_one2one ) Dog_ MVB12B ( ortholog_one2one ) GuineaPig_ MVB12B ( ortholog_one2one ) Macaque_ MVB12B ( ortholog_one2one ) Mouse_ Mvb12b ( ortholog_one2one ) Pig_ MVB12B ( ortholog_one2one ) Rat_ Mvb12b ( ortholog_one2one ) Rabbit_ MVB12B ( ortholog_one2one ) |
| Ohnologs | MVB12A |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.219089(Chimpanzee);0.211446(Mouse);NULL(Rat);0.152026(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3TOW (X-ray 1.34A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endosome {ECO:0000305}. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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