| Gene Information | |
|---|---|
| Gene Name | AP3B1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1094 |
| Protein Names | AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000132842 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00203 |
| Gene Card | AP3B1 |
| Uniprot ID | O00203 |
| Pfam | PF01602; PF14796; PF14797 |
| In ASD | no |
| Allosteric Prediction | no (-0.060982097) |
| Ortholog in Animals | Alpaca_ AP3B1 ( ortholog_one2one ) Dog_ AP3B1 ( ortholog_one2one ) GuineaPig_ AP3B1 ( ortholog_one2one ) Macaque_ AP3B1 ( ortholog_one2one ) Mouse_ Ap3b1 ( ortholog_one2one ) Pig_ AP3B1 ( ortholog_one2one ) Rat_ Ap3b1 ( ortholog_one2one ) Rabbit_ AP3B1 ( ortholog_one2one ) |
| Ohnologs | AP3B2 |
| Paralogs | AP1B1, AP4B1, AP2B1, AP3B2 |
| Tissue | pituitary.gland |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:9151686, ECO:0000269|PubMed:9182526}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121908904 rs6453373 |
| Subcellular location [CC] | Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000305|PubMed:9151686}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus {ECO:0000305|PubMed:9151686}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000305|PubMed:9151686}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |