| Gene Information | |
|---|---|
| Gene Name | SMPDL3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 455 |
| Protein Names | Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000130768 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92485 |
| Gene Card | SMPDL3B |
| Uniprot ID | Q92485 |
| Pfam | PF19272; PF00149 |
| In ASD | no |
| Allosteric Prediction | no (-0.719859112) |
| Ortholog in Animals | Alpaca_ SMPDL3B ( ortholog_one2one ) Dog_ SMPDL3B ( ortholog_one2one ) GuineaPig_ SMPDL3B ( ortholog_one2one ) Mouse_ Smpdl3b ( ortholog_one2one ) Pig_ SMPDL3B ( ortholog_one2one ) Rat_ Smpdl3b ( ortholog_one2one ) Rabbit_ SMPDL3B ( ortholog_one2one ) |
| Ohnologs | SMPDL3A |
| Paralogs | SMPDL3A, SMPD1 |
| Tissue | pancreas, lung, small.intestine |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34560878 |
| Subcellular location [CC] | Secreted {ECO:0000250}. Cell membrane {ECO:0000250|UniProtKB:P58242}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:P58242}. |
| Mouse PG classification | NA |
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