| Gene Information | |
|---|---|
| Gene Name | RNF183 |
| Organism | Homo sapiens (Human) |
| Gene Length | 192 |
| Protein Names | E3 ubiquitin-protein ligase RNF183 (EC 2.3.2.27) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000165188 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96D59 |
| Gene Card | RNF183 |
| Uniprot ID | Q96D59 |
| Pfam | PF13639 |
| In ASD | no |
| Allosteric Prediction | no (-1.599819715) |
| Ortholog in Animals | Alpaca_ RNF183 ( ortholog_one2one ) Dog_ RNF183 ( ortholog_one2one ) GuineaPig_ RNF183 ( ortholog_one2one ) Macaque_ RNF183 ( ortholog_one2one ) Mouse_ Rnf183 ( ortholog_one2one ) Pig_ RNF183 ( ortholog_one2one ) Rat_ Rnf183 ( ortholog_one2one ) Rabbit_ RNF183 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RNF223, RNF208, RNF225 |
| Tissue | NA |
| Tissue Specificity | Kidney and testis. {ECO:0000269|PubMed:29300766}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3750533 rs3750534 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:29507230}; Single-pass type IV membrane protein {ECO:0000305|PubMed:29507230}. Endoplasmic reticulum {ECO:0000269|PubMed:26567849}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:Q8QZS5}. Lysosome membrane {ECO:0000250|UniProtKB:Q8QZS5}. |
| Mouse PG classification | NA |
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