| Gene Information | |
|---|---|
| Gene Name | COG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 828 |
| Protein Names | Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3) (Vesicle-docking protein SEC34 homolog) (p94) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000136152 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96JB2 |
| Gene Card | COG3 |
| Uniprot ID | Q96JB2 |
| Pfam | PF04136 |
| In ASD | no |
| Allosteric Prediction | no (-0.87762175) |
| Ortholog in Animals | Alpaca_ COG3 ( ortholog_one2one ) Dog_ COG3 ( ortholog_one2one ) GuineaPig_ COG3 ( ortholog_one2one ) Macaque_ COG3 ( ortholog_one2one ) Mouse_ Cog3 ( ortholog_one2one ) Pig_ COG3 ( ortholog_one2one ) Rat_ Cog3 ( ortholog_one2one ) Rabbit_ COG3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in pancreas and testis and lowest levels in lung. {ECO:0000269|PubMed:11292827}. |
| Pharmacological Animal Models | 0.057672(Chimpanzee);0.056060(Mouse);NULL(Rat);0.184091(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs747042102 rs2274285 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:11292827}; Peripheral membrane protein {ECO:0000269|PubMed:11292827}. Note=Associated with the peripheral membrane of cis/medial cisternae. |
| Mouse PG classification | NA |
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