| Gene Information | |
|---|---|
| Gene Name | CNTN5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1100 |
| Protein Names | Contactin-5 (Neural recognition molecule NB-2) (hNB-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000149972 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O94779 |
| Gene Card | CNTN5 |
| Uniprot ID | O94779 |
| Pfam | PF00041; PF07679 |
| In ASD | no |
| Allosteric Prediction | no (-0.648477747) |
| Ortholog in Animals | Alpaca_ CNTN5 ( ortholog_one2one ) GuineaPig_ CNTN5 ( ortholog_one2one ) Macaque_ CNTN5 ( ortholog_one2one ) Mouse_ Cntn5 ( ortholog_one2one ) Pig_ CNTN5 ( ortholog_one2one ) Rat_ Cntn5 ( ortholog_one2one ) Rabbit_ CNTN5 ( ortholog_one2one ) |
| Ohnologs | CNTN3, CNTN6, CNTN4, CNTN2 |
| Paralogs | CNTN2, NFASC, ROBO2, SDK1, SDK2, CNTN3, HMCN2, CNTN6, DSCAML1, VSIG10L, CNTN1, IGDCC4, IGSF21, VCAM1, ROBO1, L1CAM, BOC, DCC, IGDCC3, ROBO4, IGSF9, VSIG10, DSCAM, CDON, NCAM1, ROBO3, CHL1, NRCAM, NEO1, IGSF9B, MXRA5, IGSF10, PTPRQ, NCAM2, PRTG, CNTN4 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain and kidney and at very low level in placenta. Not expressed in other tissues. In brain, it is highly expressed in the occipital lobe, amygdala, cerebral cortex, frontal lobe, thalamus and temporal lobe. Expressed at moderate level in the cerebellum, substantia nigra, putamen, medulla and hippocampus. Weakly expressed in the spinal cord and caudate nucleus. Weakly or not expressed in the corpus callosum. {ECO:0000269|PubMed:11013081}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4N68 (X-ray 1.80A ) 5E52 (X-ray 2.69A ) |
| DBSNP | rs10790978 rs7125822 rs10893933 rs11223168 rs1944169 rs1216183 rs35208161 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |