| Gene Information | |
|---|---|
| Gene Name | CNTN3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1028 |
| Protein Names | Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000113805 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9P232 |
| Gene Card | CNTN3 |
| Uniprot ID | Q9P232 |
| Pfam | PF00041; PF07679 |
| In ASD | no |
| Allosteric Prediction | no (-1.070835057) |
| Ortholog in Animals | Alpaca_ CNTN3 ( ortholog_one2one ) Dog_ CNTN3 ( ortholog_one2one ) GuineaPig_ CNTN3 ( ortholog_one2one ) Macaque_ CNTN3 ( ortholog_one2one ) Mouse_ Cntn3 ( ortholog_one2one ) Pig_ CNTN3 ( ortholog_one2one ) Rat_ Cntn3 ( ortholog_one2one ) Rabbit_ CNTN3 ( ortholog_one2one ) |
| Ohnologs | CNTN1, CNTN6, CNTN4, CNTN5, CNTN2 |
| Paralogs | CNTN5, CNTN2, NFASC, ROBO2, SDK1, SDK2, HMCN2, CNTN6, DSCAML1, VSIG10L, CNTN1, IGDCC4, IGSF21, VCAM1, ROBO1, L1CAM, BOC, DCC, IGDCC3, ROBO4, IGSF9, VSIG10, DSCAM, CDON, NCAM1, ROBO3, CHL1, NRCAM, NEO1, IGSF9B, MXRA5, IGSF10, PTPRQ, NCAM2, PRTG, CNTN4 |
| Tissue | NA |
| Tissue Specificity | In brain, it is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. {ECO:0000269|PubMed:11013081}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WJ3 (NMR - ) |
| DBSNP | rs626578 rs626578 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. |
| Mouse PG classification | NA |
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