| Gene Information | |
|---|---|
| Gene Name | CNTN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1040 |
| Protein Names | Contactin-2 (Axonal glycoprotein TAG-1) (Axonin-1) (Transient axonal glycoprotein 1) (TAX-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000184144 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q02246 |
| Gene Card | CNTN2 |
| Uniprot ID | Q02246 |
| Pfam | PF00041; PF07679 |
| In ASD | no |
| Allosteric Prediction | yes (0.55033862) |
| Ortholog in Animals | Alpaca_ CNTN2 ( ortholog_one2one ) Dog_ CNTN2 ( ortholog_one2one ) GuineaPig_ CNTN2 ( ortholog_one2one ) Macaque_ CNTN2 ( ortholog_one2one ) Mouse_ Cntn2 ( ortholog_one2one ) Pig_ CNTN2 ( ortholog_one2one ) Rat_ Cntn2 ( ortholog_one2one ) Rabbit_ CNTN2 ( ortholog_one2one ) |
| Ohnologs | CNTN1, CNTN3, CNTN6, CNTN4, CNTN5 |
| Paralogs | CNTN5, NFASC, ROBO2, SDK1, SDK2, CNTN3, HMCN2, CNTN6, DSCAML1, VSIG10L, CNTN1, IGDCC4, IGSF21, VCAM1, ROBO1, L1CAM, BOC, DCC, IGDCC3, ROBO4, IGSF9, VSIG10, DSCAM, CDON, NCAM1, ROBO3, CHL1, NRCAM, NEO1, IGSF9B, MXRA5, IGSF10, PTPRQ, NCAM2, PRTG, CNTN4 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OM5 (X-ray 3.07A ) |
| DBSNP | rs2275697 rs2229866 rs2305276 rs17416074 |
| Subcellular location [CC] | Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons. |
| Mouse PG classification | HPG |
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