| Gene Information | |
|---|---|
| Gene Name | CNTLN |
| Organism | Homo sapiens (Human) |
| Gene Length | 1405 |
| Protein Names | Centlein (Centrosomal protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000044459 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NXG0 |
| Gene Card | CNTLN |
| Uniprot ID | Q9NXG0 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.059120782) |
| Ortholog in Animals | Alpaca_ CNTLN ( ortholog_one2one ) Dog_ CNTLN ( ortholog_one2one ) Macaque_ CNTLN ( ortholog_one2one ) Mouse_ Cntln ( ortholog_one2one ) Pig_ CNTLN ( ortholog_one2one ) Rat_ Cntln ( ortholog_one2one ) Rabbit_ CNTLN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | substantia.nigra, zone.of.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3808795 rs3808794 rs3808782 rs7035276 rs2499057 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:24554434}. Note=Colocalizes with gamma-tubulin during interphase and mitosis. Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434). {ECO:0000250|UniProtKB:A9ZSY0, ECO:0000269|PubMed:24554434}. |
| Mouse PG classification | NA |
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